Research

Understanding of Tumor-Immune Dynamics for Better Cancer Immunotherapy

We are trying to understand tumor-immune dynamics to overcome immune resistance of tumors. Recent research clearly demonstrate that the immune system plays a fundamental role in combating tumors. However, fundamental questions how tumors acquire intrinsic and acquired resistance to immune-cell killing by immunotherapeutic agents including vaious checkpoint inhibitors still remain. Therefore, we aim to elucidate the multidimensional, nonlinear nature of the interaction between immune and tumor to realize the ideal goal of cancer immunotherapy.